Resources

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Breakthrough Decentralized Respiratory Trial with Pulmonary Function Testing.

Science 37 Enables a Decentralized Model in Respiratory Trial with Pulmonary Function Testing

A large biopharma company was conducting a Phase IV trial of an approved biologic to understand its potential impact on sleep disturbance associated with asthma. Toward the end of…

/Resources/science-37-metasite-action-science-37-enables-decentralized-model-respiratory-trial

The Time for Decentralized Clinical Trials is Now

The FDA Draft Guidance on Decentralized Clinical Trials provides recommendations for clinical trial sponsors to incorporate virtual elements into clinical research. Authors: Irena…

/time-decentralized-clinical-trials-now

Transform Observational Studies with a Virtual Site.

Are your observational or long-term follow-up studies facing challenges? Are keeping protocols open across multiple sites slowing down your studies? Or is loss of participant…

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How Science 37 Partners with Contract Research Organizations

As the pioneer in virtual clinical trials, Science 37 offers contract research organizations (CROs) the most experience and ability to accelerate study timelines. Through in-house…

/Resources/how-science-37-partners-contract-research-organizations

Three Ways the Metasite Model Creates Value for Dermatologic Clinical Trials

The past decade has brought an explosion of new therapies for patients with dermatologic disease. With numerous new treatments on the horizon, it is an exciting and hopeful time for…

Learn more

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How to Operationalize Dermatology Clinical Trials with a Virtual Site.

Clinical trials for dermatology can be a uniquely challenging endeavor for sponsors and clinical researchers, as it is challenging to identify and support patients who have not…

/Resources/how-operationalize-dermatology-clinical-trials-virtual-site

The Science 37 Metasite in Action: A Fully Decentralized Trial for a Rare Vascular Disorder.

A biopharma company was planning a Phase III, randomized, double-blind, placebo-controlled clinical trial for a drug to treat a rare and serious vascular disorder. Learn how the…

/Resources/science-37-metasite-action-fully-decentralized-trial-rare-vascular-disorder

Treated Like a Human, Not a Statistic

Virtual clinical trial access program provided breast cancer patients with personal, in-home treatment during the COVID-19 pandemic.

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The Science 37 Metasite in Action: How Science 37 Accelerated Enrollment for a Dermatology Trial.

A biopharma company was conducting a Phase II randomized controlled clinical trial in the United States for a dermatological condition. The trial protocol required participation by…

/Resources/science-37-metasite-action-how-science-37-accelerated-enrollment-dermatology-trial

Science 37's mission is to accelerate clinical research by enabling universal trial access for patients. As a single Metasite, we reach an expanded patient population beyond the…

The Science 37 Metasite™

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Decentralized in Action: How Science 37 Accelerated Enrollment for a Diagnostic Oncology Trial.

A biopharma company was investigating how its diagnostic screening technology—a one-time blood sample—performed against the gold standard cancer screening procedure. Download to learn…

/Resources/decentralized-action-how-science-37-accelerated-enrollment-diagnostic-oncology-trial

The Science 37 Metasite in Action: Accelerating Enrollment for an Infectious Disease Trial.

A biopharma company was conducting a phase II randomized controlled trial for an infectious disease. The protocol required the participation of high-risk comorbidity patients ages 65+…

/Resources/science-37-metasite-action-accelerating-enrollment-infectious-disease-trial

Science 37 Accelerates Timelines and Expands Reach in Infectious Disease Study.

A biotech company approached Science 37 to swiftly recruit, enroll, and treat a targeted population of participants across the United States. The study was unique due to the challenge…

/Resources/science-37-accelerates-timelines-and-expands-reach-infectious-disease-study-0

How to Save an At-Risk Clinical Trial

How can you rescue an at-risk clinical trial without compromising quality? Delays in clinical research are common and cost pharmaceutical companies exorbitant amounts of money. Four in…

/Resources/how-save-risk-clinical-trial

Top Five Reasons to Include Virtual Sites in Your Infectious Disease Research

Virtual sites can help deliver infectious disease studies more quickly, more inclusively and in a more patient-centric way.

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How to Operationalize Infectious Disease Trials with a Virtual Site.

Download our Infectious Disease Clinical Trial Playbook to discover the premier, patient-centric strategy for solving hallmark challenges in infectious disease research. In this…

/Resources/how-operationalize-infectious-disease-trials-virtual-site

4 Things to Know about the EMA’s Updated Decentralized Clinical Trial Recommendations

Studies with Decentralized Clinical Trial (DCT) elements must be fit-for-purpose—and designed to protect patient safety, privacy and rights

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Science 37 Forecast—The Adoption of Hybrid Oncology Trials Will Accelerate in 2023 and Beyond

Oncology is a therapeutic area of singular importance in clinical research. Breakthroughs in drug discovery will catalyze numerous studies for targeted cancer treatments, with Evaluate…

/science-37-forecast-adoption-hybrid-oncology-trials-will-accelerate-2023-and-beyond

Science 37 Uses the Metasite to Support Clinical Trial in Rare Neurodegenerative Disease.

An industry leading pharmaceutical company implemented the Science 37’s Metasite to reduce patient patient burden and accelerate trial timelines. Learn how the Metasite expanded reach…

/Resources/science-37-uses-metasite-support-clinical-trial-rare-neurodegenerative-disease

Science 37 Utilizes Flexibility of the Metasite Model in Study of Rare Disease.

A biotech company approached Science 37 to develop a virtualized process to evaluate patients who may be eligible for an interventional study with a novel gene therapy program for a…

/Resources/science-37-utilizes-flexibility-metasite-model-study-rare-disease

Science 37 Metasite Delivers Broad Patient Access in MDD Trial

A global leader in pharmaceuticals was looking to pilot an interventional study in major depressive disorder (MDD) using a Metasite model, in parallel to their Phase IIb trial. …

/Resources/science-37-metasite-delivers-broad-patient-access-mdd-trial

Infographic

Clinical decision makers confirm a shift to hybrid and decentralized studies.

Clinical research is undergoing transformation across the board—but how will it impact oncology clinical trials? Science 37® has surveyed research executives at trial-sponsored…

/Resources/clinical-decision-makers-confirm-shift-hybrid-and-decentralized-studies

What Clinical Trial Patient Participants Want

A new groundbreaking research study reveals the perceptions and preferences of clinical trial participants and how those determinants impact all factors of the trial lifecycle. In her…

/what-clinical-trial-patient-participants-want

Evidence From Two Parallel Depression Trials

The adoption of the Decentralized Clinical Trial model in psychiatry has been tempered by concern regarding the conduct of clinician-reported outcomes conducted by centralized raters.…

/Resources/evidence-two-parallel-depression-trials

Pharma Execs Prefer Hybrid Clinical Trials

Hybrid clinical trials continue to gain traction as stakeholders see the measurable benefits that remote study technology brings to clinical research. Read the latest blog from Drew…

/pharma-execs-prefer-hybrid-clinical-trials

How to Operationalize Oncology Trials with a Decentralized Approach

The importance of oncology in pharmaceutical research cannot be underestimated. However, oncology trials face challenges such as slow recruitment, complex protocols and frequent…

/Resources/how-operationalize-oncology-trials-decentralized-approach

Science 37 Accelerates Timelines and Expands Reach in Infectious Disease Study.

An industry-leading non profit institute was looking to execute a hybrid Phase II Randomized Controlled Study to determine the effectiveness of an interventional therapy. In this case…

/Resources/science-37-accelerates-timelines-and-expands-reach-infectious-disease-study

Decentralized Clinical Trials — Is there a Positive Return on Investment on a Virtual Site?

Across the Life Sciences industry, there has been much talk about the cost and value of decentralized clinical trials (DCT) and the potential return on investment (ROI) when the…

/Resources/Modeling-Trial-Cost-and-Timelines-to-Maximize-Decentralized-Clinical-Trial-ROI

Science 37 Accelerates Timelines and Expands Reach in Infectious Disease Study

An industry-leading non profit institute was looking to execute a hybrid Phase II Randomized Controlled Study to determine the effectiveness of an interventional therapy. In this case…

Calculate your Virtual Site ROI with a Science 37 Expert

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ROI Calculator

Schedule time with a Science 37 expert and receive personalized results on how decentralized solutions can: Accelerate timelines Save opportunity costs Increase patient enrollment…

Evaluating the Use of Backup Solutions for ePRO Systems

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Published Paper

A retrospective examination of the effectiveness, usability, and challenges with web-based electronic clinical outcome assessment (eCOA) backups.

https://www.appliedclinicaltrialsonline.com/view/evaluating-the-use-of-backup-solutions-for-epro-systems

A Long-Time Pharmaceutical Executive’s Experience Participating in a Clinical Trial

With 15 years of experience in pharmaceuticals, Science 37’s Leah Zilla thought she knew what to expect when she signed up for a traditional trial for a COVID-19 vaccine. Her…

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How Decentralized and Hybrid Trials are Impacting Clinical Research

Patient accessing teleheatlh in a decentralized clinical trial

Science 37’s 2nd Annual The Future of Clinical Trials Survey shares how the acceleration and adoption of decentralized clinical trials will reshape the research landscape in 2023.…

/decentralized-clinical-trials-trends-report-2022

Decentralized Clinical Trials—Where the Industry is Now.

The clear and hidden benefits of the hybrid and decentralized clinical trial models and how to implement agile trials to enhance clinical research.

/decentralized-clinical-trials-where-industry-now

How to Meet the FDA Diversity Action Plan Guidance

The pending FDA Guideline’s intention is clear—pharma companies must plan, report and collaborate to improve diverse representation in clinical trials. Most sponsors have assessed…

/Resources/how-meet-fda-diversity-action-plan-guidance

Why Migraine and Other Headache Disorders Are a Good Fit for Decentralized Clinical Trials

Patient accessing decentralized clinical trials

Characterized by recurring episodes of moderate to severe headache, elevated sensitivity to sound and/or light and other unpleasant symptoms, migraines can often be debilitating for…

Decentralized Clinical Trials in Oncology: Are We Ready for a Virtual-First Paradigm?

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Published Paper

In this paper, published in the Journal of Clinical Oncology, Dr. Shaalan Beg MD MS and team explore how decentralized clinical trial tools are poised to impact the oncology clinical…

https://ascopubs.org/doi/full/10.1200/JCO.22.00358

Refining, Rethinking, and Decentralizing Clinical Research

Decentralized tools and technologies will continue to provide new opportunities for patient engagement post-COVID.

/refining-rethinking-and-decentralizing-clinical-research

A More Agile Approach to Decentralized Clinical Trials

Speakers at the Agile Approach to Decentralized Clinical Trials Webinar

Why a flexible, configurable, and dynamic approach to clinical trials is the post-pandemic solution for the most innovative sponsors.

Watch here

/agile-clinical-trial

New Data on the Future of CNS Clinical Trials

In this special webinar event, Science 37 presented the results of a new study that looks at how future trends in clinical research will affect the CNS (central nervous system) space…

Watch Back

/Company/Events/webinar-new-data-future-cns-clinical-trials

The Agile Trial: A New Clinical Leadership

Traditional or decentralized–is it a binary decision? As the industry changes and evolves, we are continually asking what’s practical, what’s patient-centric, and what’s acceptable to…

Watch Back

/Company/Events/agile-trial-new-clinical-leadership

Oncology Clinical Trials: How Hybrid Approaches are Changing The Clinical Landscape

Earlier in 2022, Science 37® surveyed research executives at trial-sponsored organizations, uncovering pivotal insights on clinical research trends that are impacting the oncology…

Watch Back

/Company/Events/oncology-report-2022-video-on-demand

How Accelerating eCOA Implementation Benefits Decentralized Clinical Trials

Using eCOA on a mobile device for a decentralized clinical trial

A key benefit of decentralized clinical trials is the ability to enable faster trials, through improved patient recruitment, retention, and diversity. eCOA, when implemented correctly…

/how-accelerating-ecoa-implementation-benefits-decentralized-clinical-trials

An Executive Clinical Trial Playbook

How Decentralized and Hybrid Clinical Trials Accelerate Research and Enable Diversity While no longer a new concept, decentralized clinical trials can be challenging to comprehend…

/clinicaltrialplaybook

Decentralized Clinical Trial Technology— How to Accelerate eCOA Implementation

The key benefits of decentralized clinical trials is the ability to enable faster implementation of trials, greater speed to go live, and accelerated timelines. Electronic clinical…

/Resources/decentralized-clinical-trial-technology-how-accelerate-ecoa-implementation

Is Your Clinical Trial Technology Disconnected?

How to improve patient, site, and sponsor/CRO experience through unified technology.

https://www.science37.com/your-clinical-trial-technology-disconnected

Cancer Patients Prefer Decentralized Trials

A new industry survey shows oncology trials are embracing decentralized methods to keep patients safe, engaged, and committed.

/cancer-patients-prefer-decentralized-trials

Improving the Patient Journey & Increasing Equitable Access in Oncology Research

Accurate representations of patient populations are critical to producing reliable clinical evidence for patient care.

/improving-patient-journey-increasing-equitable-access-oncology-research

How Decentralized Clinical Trials are Impacting Oncology Research

Clinical research is undergoing transformation across the board—but how will it impact oncology clinical trials? Science 37® has surveyed research executives at trial-sponsored…

/Resources/how-decentralized-clinical-trials-are-impacting-oncology-research

A New Era of Accessible Clinical Trials

The original clinical trial laid the foundation for modern clinical studies. Thanks to the people working in clinical research, we have the opportunity to provide access to more people…

/new-era-accessible-clinical-trials

How Decentralized Clinical Trials Deliver on Diversity: A Case Study

Agile studies and fully Decentralized Clinical Trials are opening opportunities for any patient anywhere to benefit from participation in clinical research. This can have impacts on…

/Resources/how-decentralized-clinical-trials-deliver-diversity-case-study

Building Inclusive Clinical Trials for the LGBTQIA+ Community

As we consider the strides made in awareness and visibility through Pride Month, we look at our own arena, healthcare, and see a much different picture.

/building-inclusive-clinical-trials-strategies-include-lgbtqia-community

Improve Long-Term Follow-Up Studies with Decentralized Clinical Trials

Improve Long-Term Follow-Up Studies with DCT

In his latest insight brief, Gordon Cummins shares how more agile and DCT approaches can optimize the delivery of long-term follow-up studies—improving and accelerating Real World…

/Resources/improve-long-term-follow-studies-dct

A New Era of Accessible Clinical Trials

On this Clinical Trials Day, we highlight the opportunity to provide access to more people in more places and thank the people working within clinical research to make it happen.

/new-era-accessible-clinical-trials

Investing in our Mobile Nursing Network and Elevating our Nurses Voices.

This International Nurses Day we elevate the voices of our mobile nursing team and share what inspires them most about their work in decentralized clinical trials.

/investing-our-mobile-nursing-network-elevating-our-nurses-voices

New Diversity Reporting Imperatives For Clinical Trial Sponsors By Lawmakers & Regulators

The F.D.A. recommends that clinical trial sponsors develop a Race and Ethnicity Diversity Plan to inform outreach, recruitment and retention throughout the trial process.

/new-diversity-reporting-imperatives-clinical-trial-sponsors-lawmakers-regulators

Accelerate Enrollment and Enable Diversity with The Science 37 Metasite™

Traditional clinical trials exclude more than 90 percent of patients and providers because of geographic and access barriers. This leads to study delays, excessive costs, and…

/Resources/accelerate-enrollment-and-enable-diversity-science-37-metasitetm

Mobile Nursing: A Global Mobile Healthcare Network

Mobile Nursing: A Global Mobile Healthcare Provider Network

The healthcare landscape has changed, and mobile healthcare is now an integral part of clinical research. Beyond nursing, mobile healthcare must deliver more – compassion,…

/Resources/mobile-nursing-global-mobile-healthcare-network

Decentralization: An Ethical Obligation

We have the capability to reach anyone, anywhere utilizing decentralized clinical trial techniques and more agile clinical trial designs.

For more than 60 years, the traditional clinical trial model has relied on a disparate network of independent investigator sites to find, enroll, and matriculate patients through a…

/sites/default/files/2022-04/S37_InsightBrief_DecentralizationAnEthicalObligation_r3.pdf

A New Clinical Leadership—The Agile Clinical Trial

To access the full advantage of decentralized trials, sponsors have to begin the planning process with agile in mind.

/new-clinical-leadership-agile-clinical-trial

Pioneering a First-Of-It’s-Kind Decentralized Clinical Trial in Depression.

For this Phase II study of an oral investigative compound, Science 37® embarked on a journey to design the first ever decentralized clinical trial (DCT) in depression.

There is a significant unmet medical need for patients with Major Depressive Disorder (MDD) who either do not respond to, or do not tolerate, current augmentation approaches for…

/Resources/pioneering-first-its-kind-decentralized-clinical-trial-depression

Benefits of DCT technology, mobile nursing and connected devices on pediatric clinical trials

Combining Decentralized Clinical Trial Technology, Effective Mobile Nursing and Connected Devices To Deliver Pediatric Clinical Trials At Home

At DIA Europe 2022, Senior Director of Nursing Solutions for Science 37, Brianne Peters presented a poster on Combining DCT Technology, Effective Mobile Nursing and Connected Devices…

/Resources/combining-dct-technology-effective-mobile-nursing-and-connected-devices-deliver-pediatric

Enhancing CNS Studies with Agile and Decentralized Clinical Trials

CNS clinical trials are among the fastest-growing adopters of decentralization.

/enhancing-cns-studies-agile-and-decentralized-clinical-trials

Breaking Through Mistrust to Better Mental Health in Black Communities

Can the future of ending health disparities and improving health outcomes for Black Americans be in participation in clinical trials? What role does mental health play in current and future health outcomes? A panel of experts discuss.

What role does mental health play in current and future health outcomes? A panel of experts discuss.

/breaking-through-mistrust-better-mental-health-black-communities

Decentralized Model Delivers in Major Depressive Disorder Clinical Trial

A global leader in pharmaceuticals was looking to pilot the same interventional study in major depressive disorder (MDD) using a decentralized clinical trial (DCT) model to evaluate operational feasibility, data quality, enrollment speed, and retention. Science 37 helped expand reach beyond the confines of traditional sites, reaching patients who otherwise were unable to access the trial.

In parallel to their Phase IIb trial, a global leader in pharmaceuticals was looking to pilot the same interventional study in major depressive disorder (MDD) using a decentralized…

/Resources/decentralized-model-delivers-major-depressive-disorder-clinical-trial

Powering Rare Disease Research with Agile, Decentralized and Patient- Centric Approaches.

Clinical trials for rare diseases have always presented challenges. From investigator training to data collection, conducting clinical research for orphan disorders is mired with condition-specific challenges that slow development and place an enormous burden on patients wanting to participate in a potentially life-saving clinical trial.

Through the rapidly increasing trend of agile, patient-centric approaches, we can address the distinctive challenges for patients with rare diseases. Travel may be difficult. Many are…

/Resources/powering-rare-disease-research-agile-decentralized-and-patient-centric-approaches-0

Making Rare Disease Research Easier for Patients, Easier for Everyone

Through the rapidly increasing trend of patient-centric research, we can address the distinctive challenges for patients with rare diseases. Travel may be difficult. Many are children…

/Resources/making-rare-disease-research-easier-patients-easier-everyone

How Agile Clinical Trials are Impacting CNS Research

How will decentralization impact CNS (central nervous system) clinical trials? Science 37 has surveyed research executives at trial-sponsoring organizations, uncovering pivotal insights on how clinical research trends are impacting the CNS space.

We know that clinical research is undergoing transformation across the board—but how will it impact CNS (central nervous system) clinical trials? Science 37® has surveyed research…

/Resources/how-agile-clinical-trials-are-impacting-cns-research

Powering Rare Disease Research with Agile, Decentralized and Patient-Centric Approaches

Here are key takeaways from a recent Science 37-hosted rare disease-focused webinar:

/powering-rare-disease-research-agile-decentralized-and-patient-centric-approaches

Centralize Clinical Trials with Decentralized Clinical Trials.

As the industry adopts more agile and decentralized approaches, it has rallied around the term decentralized clinical trials and expanded its definition to include all mobile, remote,…

Are you prepared for the DEPICT Act? The industry is making significant headway in delivering diversity in clinical trials, and the time to do more is now.   On February 3, 2022, Rep…

/sites/default/files/2022-05/Decentralized_Clinical_Trials_Insight_Brief_d01.pdf

The DEPICT Act

/Resources/depict-act

Motivated by the Urgency for a Better Way: Researcher, Joannie Hayes’s Background Fuels Her Work and Reflection on Black History Month

/motivated-urgency-better-way-researcher-joannie-hayess-background-fuels-her-work-and-reflection

The Heart of a Researcher: Science-Centered Nortorious Coleman-Taylor Highlights the Importance of Black History Month

As a child Nortorious thought she wanted to be a doctor. While in school, however, she uncovered her true passion—research—studying science to help prevent people from avoiding poor health. Her heart as a researcher fuels her perspective about Black History Month and the importance of studying and honoring those who came before us as we work toward a better future.

/heart-researcher-science-centered-nortorious-coleman-taylor-highlights-importance-black-history

Reshaping Clinical Trials in 2022

learn more about reshaping trials in 2022, click here to download our latest report

/reshaping-clinical-trials-2022

Privacy By Design Protects Clinical Trial Participants

Happy Data Privacy Day! But, really, isn’t every day privacy day? As Science 37’s Privacy Officer, I certainly take that approach. Protecting the privacy rights and freedoms of…

/privacy-design-protects-clinical-trial-participants

How Access to the HPV Vaccination is helping to Eliminate Cervical Cancer

With the arrival of Cervical Health Awareness Month, comes news out of the U.K. that The human papillomavirus, or HPV, the vaccine is cutting cases of cervical cancer by nearly 90%.

/how-access-hpv-vaccination-helping-eliminate-cervical-cancer

Working with Native Americans to Navigate the COVID-19 Crisis

This Native American Heritage Month, we take a look at how the COVID-19 crisis has highlighted long standing inequities, as well as the fight to overcome them.

/Resources/Working-with-Native-Americans-to-Navigate

Enabling Diversity in Cancer Screening Study

We take a bespoke approach to all our trials. We understand every therapeutic area is different. We performed a careful review of trial design, inclusion/exclusion criteria, and review…

/Resources/enabling-diversity-cancer-screening-study

Ensuring Diversity in a COVID-19 study

We take a bespoke approach to all our trials. We understand every therapeutic area is different. We perform careful review of trial design, inclusion/exclusion criteria, and review of…

/Resources/ensuring-diversity-covid-19-study

The Decentralized Clinical Trial Operating System

A requisite, technology-first platform with limitless configurations to enable clinical research.

/DCT-OS-Report

Clinical Research in the COVID-19 Era: Methods for Continuity

Adjust ongoing trials and have the changes expeditiously reviewed by an accredited IRB.

/Covid-19

Empowering Diversity in Clinical Trials

Diverse audiences want to participate in clinical trials but so often, are not asked, overlooked, or unable to access because of geographic barriers. The Diversity in Clinical Trials…

/Resources/empowering-diversity-clinical-trials

Navigating Clinical Trials in the Coronavirus Era

Explore approaches to mitigate risks to patient safety in ongoing clinical trials.